In the beginning of the year 1665 I found the method of approximating series and the rule for reducing any dignity [power] of any binomial to such a series [ i.e. the binomial theorem ]. The same year in May I found the method of tangents of Gregory and Slusius, and in November had the direct method of Fluxions [i.e. the elements of differential calculus], and the next year in January had the Theory of Colours, and in May following I had entrance into the inverse method of Fluxions [i.e. integral calculus], and in the same year I began to think of gravity extending to the orb of the moon … and having thereby compared the force requisite to keep the Moon in her orb with the force of gravity at the surface of the earth, and found them to answer pretty nearly. All this was in the two years of 1665 and 1666, for in those years I was in the prime of my age for invention and minded Mathematicks and Philosophy more than at any time since.

What It Means

This is a placeholder explanation generated by the low-overhead model. It interprets "In the beginning of the year 1665 I found the method of approximating series and the rule for reducing any dignity [power] of any binomial to such a series [ i.e. the binomial theorem ]. The same year in May I found the method of tangents of Gregory and Slusius, and in November had the direct method of Fluxions [i.e. the elements of differential calculus], and the next year in January had the Theory of Colours, and in May following I had entrance into the inverse method of Fluxions [i.e. integral calculus], and in the same year I began to think of gravity extending to the orb of the moon … and having thereby compared the force requisite to keep the Moon in her orb with the force of gravity at the surface of the earth, and found them to answer pretty nearly. All this was in the two years of 1665 and 1666, for in those years I was in the prime of my age for invention and minded Mathematicks and Philosophy more than at any time since." in the context of "Isaac Newton (ca. 1716) A Catalogue of the Newton MSS., Portsmouth Collection, Cambridge (1888) as quoted in Sir Sidney Lee (ed.), The Dictionary of National Biography Vol.40 (1894)" to mean that wisdom is timeless.